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The discovery, described in a very examine posted March 23 in Nature, could improve the life of tens of millions who have problems with airway obstruction on account of surplus mucus.

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The group centered on blocking a protein named synaptotagmin-two, or Syt2. Syt2 is discovered within the surface area in the granules that contains mucin. Fusion of such granules With all the mobile membrane will depend on Syt2 interacting with proteins within the mobile membrane.

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SP9 reduced mucin secretion by all-around 80% and mucus accumulation in the airways by a third. Notably, it didn’t interfere with the sp9 traditional, slower mechanism that secretes a low volume of mucin constantly to protect the lungs.

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In the right quantities, at the correct consistency, mucus is really a lung’s best friend. But if there’s too much of it, or if it’s far too sticky, it might betray the organ it was intended to serve.

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